人物履歷
1982年畢業(yè)于山東農(nóng)業(yè)大學(xué);
先后獲山東農(nóng)業(yè)大學(xué)農(nóng)學(xué)碩士和中國農(nóng)業(yè)大學(xué)理學(xué)博士學(xué)位;
1989年2月至6月赴丹麥哥本哈根研修種子技術(shù);
1992年1月至1996年1月赴美國加利福尼亞大學(xué)戴維斯分校植物生物學(xué)系留學(xué),主要從事植物分子生物學(xué)方面的研究;
2001年作為教育部選派的高級(jí)訪問學(xué)者赴美國北卡羅萊納大學(xué)合作研究,主要進(jìn)行了轉(zhuǎn)基因表達(dá)調(diào)控的研究。
中國共產(chǎn)黨山東省第十一屆委員會(huì)委員。
任免信息
2018年6月24日,中國共產(chǎn)黨山東省第十一屆委員會(huì)第五次全體會(huì)議通過,決定遞補(bǔ)十一屆省委候補(bǔ)委員鄭成超同志為十一屆省委委員。[1]
學(xué)術(shù)兼職
山東生物化學(xué)與分子生物學(xué)學(xué)會(huì)副理事長
《植物學(xué)報(bào)》編委
《農(nóng)業(yè)生物技術(shù)學(xué)報(bào)》編委
所獲榮譽(yù)
2004年入選國家“
新世紀(jì)
百千萬人才工程”國家級(jí)人才[2];2007年入選
教育部“長江學(xué)者創(chuàng)新團(tuán)隊(duì)
”帶頭人;泰山學(xué)者特聘教授
2008年入選
有突出貢獻(xiàn)的中青年專家
;1996年,獲山東省“青春立功”一等功;
山東省新長征突擊手稱號(hào)。
科研項(xiàng)目
主持承擔(dān)了國家“
863
”、國家“ 973
”、國家轉(zhuǎn)基因植物研究專項(xiàng)
、國家自然科學(xué)基金、教育部博士點(diǎn)科研基金
等多項(xiàng)課題。鄭成超
1、國家轉(zhuǎn)基因植物研究專項(xiàng)《植物葉片高效特異表達(dá)啟動(dòng)子及 表達(dá)載體的研制》;2、國家“863”計(jì)劃項(xiàng)目《棉花耐鹽基因的分離、功能鑒定與應(yīng)用》;
3、國家“973”計(jì)劃項(xiàng)目《作物應(yīng)答高鹽、低溫脅迫的分子調(diào)控機(jī)理》;
4、國家自然科學(xué)基金《PNZIP基因的生物學(xué)功能鑒定與分析》;
5、國家自然科學(xué)基金《擬南芥轉(zhuǎn)錄因子AT103突變體分離及其功能研究》;
6、國家自然科學(xué)基金《一個(gè)新型棉花CCCH鋅指轉(zhuǎn)錄因子的功能鑒定與分析》;
7、教育部“長江學(xué)者創(chuàng)新團(tuán)隊(duì)發(fā)展計(jì)劃”《作物高產(chǎn)優(yōu)質(zhì)的生理與分子基礎(chǔ)》2007-2009;
8、國家轉(zhuǎn)基因?qū)m?xiàng)《作物抗除草劑抗逆基因克隆》1998-2003;
9、國家自然科學(xué)基金《擬南芥miRNA169家族及靶基因的功能鑒定與分析》2010-2013
申請(qǐng)專利
在重要功能基因、特異啟動(dòng)子克隆與功能鑒定等方面均獲得了許多擁有我國自主知識(shí)產(chǎn)權(quán)的研究成果,申請(qǐng)專利8項(xiàng)
注冊(cè)基因
克隆并在GenBank注冊(cè)基因36個(gè)。
教學(xué)工作
主講
本科生《Gene cloning and DNA analysis》、《基因工程實(shí)驗(yàn)》;
碩士生《生物化學(xué)與分子生物學(xué)專業(yè)英語》;
博士生《生物化學(xué)與分子生物學(xué)專題討論》;
招收生物學(xué)博士后。
研究方向
1.植物重要功能基因的克隆、鑒定與利用:
以重要農(nóng)作物小麥、玉米、棉花、煙草以及模式植物擬南芥為研究材料,克隆與作物發(fā)育、抗逆性等密切相關(guān)的功能基因,探討這些基因的表達(dá)模式及其調(diào)控機(jī)制,研究其在作物遺傳改良上的利用價(jià)值,獲得擁有我國自己專利或知識(shí)產(chǎn)權(quán)的基因,為生物技術(shù)育種提供基因資源。2.基因表達(dá)調(diào)控元件的鑒定與應(yīng)用:
人為控制外源基因在轉(zhuǎn)基因作物的特定器官、特定時(shí)期表達(dá),必須依靠組織專一型啟動(dòng)子、發(fā)育誘導(dǎo)型啟動(dòng)子和其它基因表到調(diào)控元件。本方向主要研究各類啟動(dòng)子的表達(dá)調(diào)控機(jī)制和應(yīng)用,染色質(zhì)重塑與基因表達(dá),核基質(zhì)結(jié)合序列MAR(matrix attachment region)對(duì)轉(zhuǎn)基因表達(dá)的調(diào)控機(jī)制與應(yīng)用。主要論文
在《
Molecular Cell
》[3](影響因子14.178
)、《 Neuclear Acids Research
》、《 Plant
Physiology》、《 New Phytologist
》、《 中國科學(xué)
》、《 科學(xué)通報(bào)
》等國內(nèi)外著名學(xué)術(shù)刊物上發(fā)表論文170多篇。1、Zheng CC, Porat R, Lu P, O’Neill SD. PNZIP is a novel mesophyll-specific cDNA that is regulated by phytochrome and a circadian rhythm and encodes a protein with a leucine zipper motif. Plant Physiology, 1998, 116:27~35
2、Zheng CC, Bui AQ, O’Neill SD. Abundance of an mRNA encoding a HMG DNA-binding protein is regulated by light and an endogenous rhythm. Plant Molecular Biology. 1993, 23:813~823
3、張可偉,鄭成超(通訊作者)。強(qiáng)MAR的分離及體外功能鑒定。科學(xué)通報(bào),2002,47(20):1572- 1577
4、楊宇濤,鄭成超(通訊作者)。一個(gè)光合組織特異表達(dá)強(qiáng)啟動(dòng)子的分離及功能分析。中國科學(xué),2003,33(4):298-306.
5、李宏,鄭成超(通訊作者)。6個(gè)植物MARs序列的ARS功能鑒定與分析。科學(xué)通報(bào),2003,48(24):2544- 2548
6、Ning Liu, Cheng-Chao Zheng(通訊作者), NTZIP antisense plants show reduced chlorophyll levels, Plant Physiology and Biochemistry. 2004,42(4):321-327
7、Changai Wu, Zheng Chengchao(通訊作者). The cotton GhNHX1 gene encoding a novel putative tonoplast Na+/H+ antiporter plays an important role in salt stress. Plant and Cell Physiology, 2004,45(5): 489-496
8、Hai-Yan Li, Cheng-Chao Zheng(通訊作者). Colonization by the Arbuscular Mycorrhizal Fungus Glomus versiforme Induces a Defense Response Against the Root-knot Nematode Meloidogyne incognita in the Grapevine (Vitis amurensis Rupr.), Which Includes Transcriptional Activation of the Class III Chitinase Gene VCH3. Plant and Cell Physiology, 2006, 47(1): 154–163
9、Xiao Wang, Chengchao Zheng(通訊作者). Isolation and purification of honokiol and magnolol from cortex magnoliae officinalis by high-speed counter-current chromatography. Journal of chromatography A. 2004, 1036(2):171-175.
10、Xiao Wang, Chengchao Zheng(通訊作者) An efficient new method for extraction, separation and purification of psoralen and isopsoralen from Fructus Psoraleae by supercritical fluid extraction and high-speed counter-current chromatography。Journal of chromatography A. 2004,.1055:135-140
11、Xiao Wang, Chengchao Zheng(通訊作者). Application of preparative high-speed counter-current chromatography for separation and purification of arctiin from Fructus Arctii, Journal of chromatography A. 2004, 1063: 247-251
12、Hua Xue, Cheng-Chao Zheng(通訊作者), TM2, a novel strong matrix attachment region isolated from tobacco, increases transgene expression in transgenic rice calli and plants. Theoretical and Applied Genetics. 2005, 110:620-627
13、Hongxin Zhang and Cheng-Chao Zheng(通訊作者).Expression and characterization of Helicobacter pylori heat-shock protein A (HspA) protein in transgenic tobacco (Nicotiana tabacum) plants. Biotechnology and Appllied Biochemistry. 2006,43, 33–38
14、 Da-Peng Shan, Jin-Guang Huang, Yu-Tao Yang, Ying-Hui Guo and
Cheng-Chao Zheng*
. Cotton GhDREB1 increases plant tolerance to low temperature and is negatively regulated by gibberellic acid. New Phytologist
2007. 176: 70–8115、Meng-Meng Zhanga, Lu-Sha Ji, Hua Xue, Yu-Tao Yang, Chang-Ai Wu and
Cheng-Chao Zheng*
. High transformation frequency of tobacco and rice via Agrobacterium-mediated gene transfer by flanking a tobacco matrix attachment region Physiologia Plantarum
2007.129: 644–651.16、Dong Wang, Yinghui Guo, Changai Wu, Guodong Yang, Yingying Li and
Chengchao Zheng*
. Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice. BMC Genomics
2008, 9:4417、Hanhua Liu, Xin Tian, Yanjie Li, Changai Wu and
Chengchao Zheng*
.Microarray-based analysis of stress-regulated microRNAs in Arabidopsis thaliana. RNA
2008, 14: 836-84318、 Xin Huang · Wei Zhu · Silan Dai · Shupeng Gai ·Guosheng Zheng ·
Chengchao Zheng
*. The involvement of mitochondrial phosphate transporter in accelerating bud dormancy release during chilling treatment of tree peony (Paeonia suVruticosa). Planta
2008, 228(4):545-5219、Xiyan Yu, Xiufeng Wang, Wenqian Zhang, Tingting Qian, Guimin Tang, Yankui Guo,
Chengchao Zheng
*. Antisense Suppression of an Acid Invertase Gene (MAI1) in Muskmelon Alters Plant Growth and Fruit Development. Journal of Experimental Botany
.2008, 59(11):2969-77.20、Jiedao Zhang, Longtao Lu, Lusha Ji, Guodong Yang,
Chengchao Zheng
*. Functional characterization of a tobacco matrix attachment region-mediated enhancement of transgene expression. Transgenic Research.
2009, 18:377-38521、 Hongxin Zhang and
Cheng-Chao Zheng
* Oral immunogenicity and protective ef?cacy in mice of a carrot-derived vaccine candidate expressing UreB subunit againstHelicobacter pylori.Protein Expression and Purification
. 2009, 69:127-13122、Tongtong Xue, Xinzheng Li, Wei Zhu, Changai Wu, Guodong Yang, and
Chengchao Zheng*
. Cotton metallothionein GhMT3a, a reactive oxygen species scavenger, increased tolerance against abiotic stress in transgenic tobacco and yeast. Journal of Experimental Botany
.2009, 60: 339-34923、 Ying-Hui Guo, Yue-Ping Yu, Dong Wang, Chang-Ai Wu, Guo-Dong Yang, Jin-Guang Huang and
Cheng-Chao Zheng*
. GhZFP1, a novel CCCH-type zinc finger protein from cotton, enhances salt stress tolerance and fungal disease resistance in transgenic tobacco by interacting with GZIRD21A and GZIPR5. New Phytologist
2009, 183: 62–7524、Yu-Tao Yang, Yan-Li Yu, Guo-Dong Yang, Jie-Dao Zhang and
Cheng-Chao Zheng*
, Tissue-specific expression of the PNZIP promoter is mediated by combinatorial interaction of different cis-elements and a novel ranscriptional factor. Nucleic Acids Research
2009, 37(8):2630–264425、Jin-Guang Huang, Mei Yang, Pei Liu, Guo-Dong Yang, Chang-Ai Wu and
Cheng-Chao Zheng*
.GhDREB1enhances abiotic stress tolerance, delays GA-mediated development and represses cytokinin signaling in transgenic Arabidopsis. Plant, Cell & Environment
, 2009, 32, 1132–114526、YanLi Yu, YanZe Li, LingLi Li, JinXing Lin,
ChengChao Zheng*
Overexpression ofPwTUA1, a pollen-specific tubulin gene, increases pollen tube elongation by altering the distribution of α-tubulin and promoting vesicle transport. Journal of Experimental Botany
,
2009, 60(9):2737-4927、 Yanjie Li, Yaru Fu, Lusha Ji, Changai Wu,
Chengchao Zheng*.
Characterization and expression analysis of the Arabidopsis mir169 family. Plant Science
2010,178: 271-28028、Jin-Guang Huang, Mei Yang, Pei Liu, Guo-Dong Yang, Chang-Ai Wu,
Cheng-Chao Zheng*.
Genome-wide profiling of developmental, hormonal or environmental responsiveness of the nucleocytoplasmic transport receptors in Arabidopsis. Gene.
2010, 451:38-4429、Dongmei Xi, Wushuang Liu, Guodong Yang, Changai Wu,
Cheng-chao Zheng*
. Seed-specific overexpression of antioxidant genes in Arabidopsis enhances oxidative stress tolerance during germination and early seedling growth. Plant Biotechnology Journal,
2010, 8:796-806.30、 Hao Huan, Sheng-Dong Qi, Fang Qi, Chang-Ai Wu, Guo-Dong Yang and
Cheng-Chao Zheng*
. NtKTI1, a Kunitz trypsin inhibitor with antifungal activity from Nicotiana tabacum, plays an important role in tobacco’s defense response. FEBS Journal
2010, 277:4076-4088 .
31、Yanjie Li, Yaru Fu, Jinguang Huang, Changai Wu and
Chengchao Zheng*
Insight into the transcriptional regulation during the early development of the maize brace root. FEBS Journal
2010